12 CLINICAL PHARMACOLOGY

Please click here for full Prescribing Information and Patient Information. It’s a medicine that belongs to a group of drugs known as phosphodiesterase type 5 inhibitors, or PDE5 for short. These medicines, which includes Sildenafil help men who suffer erectile dysfunction get and maintain an erection suitable for sex. They work by opening the blood vessels in the penis, the increased blood flow helps maintain an erection.

• Sildenafil generic is a cheaper alternative to Viagra for erectile dysfunction treatment.
• Generic sildenafil contains the same active ingredient as branded versions.
• It is approved by regulatory authorities like the FDA for safety and efficacy.
• Generic sildenafil is available in various dosages, typically 25mg, 50mg, and 100mg.
• The availability of sildenafil generics increases affordability for many patients.
• Always purchase from reputable pharmacies to ensure genuine medication.

Sildenafil is the drug contained in several products, including Viagra Connect and Viagra. Sildenafil, or as some people know it Generic Viagra has been available since 2013, helping men get great value, low-cost treatment for their ED. Sildenafil Citrate is just the technical name for Sildenafil. Medicines are often poorly absorbed by the body and so they are administered as a salt form (Citrate) to improve their effectiveness. You will often see references to Sildenafil Citrate and Sildenafil all over the internet but be assured that all Sildenafil is Sildenafil Citrate. At Travelpharm we refer to our Sildenafil Citrate erectile dysfunction medicines as Sildenafil, or Generic Viagra. Sildenafil is 200mg sildenafil citrate licenced exclusively for the treatment of male erectile dysfunction and can be used in adults over 18 years old. This product should not be used by women. There is no upper age limit for Sildenafil but physical limitations and a patient’s medical health will play a part in deciding whether sex, which can be strenuous cardiovascular exercise is appropriate or suitable. Sildenafil should be used when sex is anticipated. It should ideally be taken 30-60 minutes before sex on an empty stomach or after a light meal. If this is the first time using Sildenafil 100mg, then we would recommend you start with Sildenafil 50mg tablets initially. If they are ineffective then try 100mg next time.

• Sildenafil generic works by relaxing blood vessels in the penis for an erection.
• It is not an aphrodisiac and requires sexual stimulation to work.
• The onset of action for sildenafil generic is about 30 minutes after ingestion.
• Common side effects include headaches, flushes, and nasal congestion.
• Patients with heart issues should seek medical advice before using sildenafil.
• Sildenafil generics do not protect against sexually transmitted infections.

Dose: One tablet when required 30-60 minutes before sex is anticipated.Maximum Dose: One tablet (100mg) daily.

• Sildenafil generic is a popular choice for ED treatment worldwide.
• It provides a less expensive yet effective solution for erectile issues.
• The drug's popularity has increased due to patent expiration of brand-name Viagra.
• Always check for proper licensing and approval before purchasing.
• Consulting a healthcare provider ensures the correct dosage and safety.
• Many online sources offer genuine sildenafil generics with verified credentials.

Sildenafil 100mg tablets can be used safely every day, but we would recommend you consider alternative products like Tadalafil 5mg if this is the case. Duration of Action: approximately 4 hours Maximum Supply: 64 tablets (8 boxes) Active Ingredient: Each tablet contains Sildenafil 100mg.

• Sildenafil generic is classified as a phosphodiesterase type 5 inhibitor.
• It can be prescribed for pulmonary hypertension as well as erectile dysfunction.
• The drug should not be combined with nitrates due to severe blood pressure drops.
• Overdose symptoms include severe hypotension, dizziness, and vision changes.
• Storage should be in a cool, dry place away from children and pets.
• Always follow the prescribed dosage and do not exceed recommended limits.

Inactive ingredients: these vary between brands, for further information please speak with our pharmacist.

What other drugs will affect sildenafil?

Do not take Sildenafil tablets if you take any other medicines called “nitrates.” Nitrates are used to treat chest pain (angina). A sudden drop in blood pressure can cause you to feel dizzy, faint, or have a heart attack or stroke. Do not take Sildenafil tablets if you take medicines called guanylate cyclase stimulators such as riociguat. Please click here for more Important Risk Information. Tell all your healthcare providers that you take Sildenafil tablets.

Less common

If you need emergency medical care for a heart problem, it will be important for your healthcare provider to know when you last took Sildenafil tablets. Ask your doctor if your heart is healthy enough to handle the extra strain of having sex. Sildenafil tablets does not protect you or your partner from getting sexually transmitted diseases, including HIV—the virus that causes AIDS. Please click here for more Important Risk Information Do not take Sildenafil tablets more than one time each day. If you are concerned that you are having side effects related to the medication, please consult your doctor. This medicine is not suitable for patients who: Take medicines containing nitrates including, Nicorandil as this could reduce your blood pressure to a dangerous level.

Product	Dosage	Quantity + Bonus	Price
Viagra Generic	200mg	30 + 2 Pills	83.07€ 79.11€	Buy
Viagra Generic	25mg	60 + 4 Pills	71.99€ 68.56€	Buy
Viagra Generic	25mg	30 + 4 Pills	47.97€ 45.69€	Buy
Viagra Generic	150mg	90 + 6 Pills	147.18€ 140.17€	Buy
Viagra Generic	50mg	30 + 4 Pills	54.26€ 51.68€	Buy
Kamagra	100mg	84 + 6 Pills	264.44€ 251.85€	Buy
Viagra Generic	50mg	120 + 6 Pills	129.64€ 123.47€	Buy
Kamagra	100mg	60 + 4 Pills	201.34€ 191.75€	Buy
Viagra Generic	100mg	60 + 4 Pills	96.36€ 91.77€	Buy
Viagra Generic	50mg	360 + 10 Pills	225.33€ 214.60€	Buy
Viagra Generic	200mg	270 + 10 Pills	379.76€ 361.68€	Buy
Viagra Generic	25mg	10 Pills	25.19€ 23.99€	Buy

Are using any drugs known as nitric oxide donors, such as amyl nitrate which often used recreationally. Are allergic to sildenafil or any other ingredients listed in the patient information leaflet.

Side Effect	Frequency	Severity	Recommended Action
Headache	Common	Mild	Over-the-counter analgesics
Flushing	Common	Mild	Cooling measures
Dizziness	Less common	Mild	Rest, caution while standing
Nasal Congestion	Common	Mild	Decongestants as advised
Visual Disturbance	Rare	Mild	Seek medical advice if persists

Suffer from severe heart or liver problems. Have recently had a stroke or heart attack Have a rare inherited eye disease called retinitis pigmentosa Have ever suffered a loss of vision due to non-arteritic ischaemic optic neuropathy. Have suffered priapism (prolonged painful erection) or suffer from anatomical deformations of the penis, for example, Peyronie’s disease and Cavernosal Fibrosis. Sildenafil tablets should be used with caution in patients who suffer from low blood pressure. Most patients who use Sildenafil 100mg tablets will not experience any side effects, but some of the very common (more than 1 in 10) and common (less than 1 in 100) include: This list is not exhaustive and for less common side effects please refer to the patient information leaflet. To ensure we can offer the best price online for our Sildenafil we will often change the supplier of our generic Viagra. Whilst the packaging may vary we can assure you that the active ingredient will remain identical and we only use UK licenced medicines from UK wholesalers.

Dosage Tips	Recommended Timing	Food Interaction
Take on an empty stomach	30-60 minutes before activity	Avoid heavy, fatty meals, which delay absorption
Do not exceed prescribed dose	Do not take more than once daily	Alcohol may reduce effectiveness and increase side effects
Follow prescribed instructions	As advised by healthcare provider	Grapefruit juice may interact with metabolism

Typically we would stock brands of Sildenafil like TEVA, Mylan, Dr Reddy’s, Sandoz, Torrent and others. Simply add the number of boxes you wish to purchase, up to the maximum of 8 packs (32 tablets) and click “Add to Basket”. You will be presented with a series of questions will later be reviewed by our prescriber. Details of the prescriber on duty can be found in the footer of the website. If we have any problems with your order one of the team will get in touch and should the medicine not be suitable a full refund will be promptly issued. This medicine should be stored away from direct sunlight, and below 25C. To ensure your medicine is at its best we would advise against storing medicines on window sills (due to direct sunlight) or the bathroom (due to the humidity). Store in the original packaging, preferably in a cupboard at room temperature. This medicine should not be kept in the fridge.

13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility

Sildenafil tablets are not for use in women or children. It is not known if Sildenafil tablets are safe and effective in women or children under 18 years of age. Depending on your needs, your doctor will prescribe either a dose of 25 mg, 50 mg, or 100 mg. Take Sildenafil tablets exactly as your healthcare provider tells you to take it. Your healthcare provider will tell you how much Sildenafil tablets to take and when to take it.

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Take Sildenafil tablets about 1 hour before sexual activity. You may take Sildenafil tablets between 30 minutes to 4 hours before sexual activity if needed. Sildenafil tablets can be taken with or without food. If you take Sildenafil tablets after a high fat meal (such as a cheeseburger and french fries), Sildenafil tablets may take a little longer to start working. Sildenafil tablets can cause your blood pressure to drop suddenly to an unsafe level if it is taken with certain other medicines. At Travelpharm we offer FREE delivery on most orders over £35, we aim to provide the best price and service at all times. With genuine products dispensed from our UK pharmacy, we aim to offer a website and service that strives to help you choose the most efficient, suitable medicines for you and your family.View our GPhC registration: 9012214 If you are a consumer or patient please visit this version. HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use SILDENAFIL TABLETS safely and effectively. See full prescribing information for SILDENAFIL TABLETS.SILDENAFIL tablets, for oral useInitial U.S. Approval: 1998INDICATIONS AND USAGEAdultsSildenafil tablets are a phosphodiesterase-5 (PDE-5) inhibitor indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening.

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Tell your doctor about all other medications you use for erectile dysfunction. Ask your healthcare provider or pharmacist for a list of these medicines if you are not sure. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine. Other drugs may interact with sildenafil, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Drug details

Store sildenafil tablets and oral film at room temperature, between 20°C and 25°C (68°F and 77°F). Store sildenafil reconstituted oral suspension below 30°C (86°F) or in a refrigerator between 2°C to 8°C (36°F to 46°F). Throw away the reconstituted oral suspension after 60 days. Active ingredient: sildenafil citrateInactive ingredients: dextrose and water for injection. Contains no ingredients made from gluten-containing grain (eg, wheat, barley, or rye). (1)DOSAGE AND ADMINISTRATIONAdults: 20 mg three times a day. (2.1)DOSAGE FORMS AND STRENGTHSTablets: 20 mg (3)CONTRAINDICATIONSWARNINGS AND PRECAUTIONSVasodilation effects may be more common in patients with hypotension or on antihypertensive therapy. (5.1)Use in pulmonary veno-occlusive disease (PVOD) may cause pulmonary edema and is not recommended. (5.2)Hearing or visual impairment: Seek medical attention if sudden decrease or loss of vision or hearing occurs. (5.4, 5.5)Pulmonary hypertension (PH) secondary to sickle cell disease: Sildenafil citrate may cause serious vaso-occlusive crises. (5.8)ADVERSE REACTIONSDRUG INTERACTIONSUse with strong CYP3A inhibitors: Not recommended. ( 7, 12.3)Concomitant PDE-5 inhibitors: Avoid use with Viagra ®or other PDE-5 inhibitors.

Publication types

Revatio is distributed by Pfizer Labs, Division of Pfizer Inc., NY, NY 10017. Viagra is distributed by Pfizer Labs, Division of Pfizer Inc., NY, NY 10017. It is distributed by: IBSA Pharma Inc, Parsippany, NJ 07054 USA. Cialis vs Viagra - What's the difference between them? Do you know these 11 amazing facts about Viagra?

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Is generic Viagra available in the U.S.? Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Sildenafil tablet is a prescription medicine used to treat erectile dysfunction (ED). You will not get an erection just by taking this medicine. Sildenafil tablets help a man with erectile dysfunction get and keep an erection only when he is sexually excited (stimulated).