Sanofi and Lilly Agree To Pursue Regulatory Approval Of Nonprescription Cialis

13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility
17.3 Cardiovascular Considerations
17.5 Potential for Drug Interactions When Taking CIALIS for Once Daily Use
14.4 CIALIS 5 mg for Once Daily Use for ED and BPH
17.10 Sexually Transmitted Disease
Further information
14.1 CIALIS for Use as Needed for ED

"Millions of men worldwide trust Cialis to treat ED.

13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility

We are pleased to work with Sanofi to pursue a path that could allow more men who suffer from ED to obtain convenient access to a safe and reliable product without a prescription," said David Ricks, senior vice president, Lilly, and president, Lilly Bio-Medicines.

Product	Dosage	Quantity + Bonus	Price
Cialis Generic	5mg	360 + 10 Pills	268.08€ 255.31€
Cialis Soft Tabs	20mg	180 + 8 Pills	353.17€ 336.35€
Cialis Generic	5mg	10 Pills	29.39€ 27.99€
Cialis Generic	10mg	90 + 6 Pills	146.17€ 139.21€
Cialis Original	20mg	14 + 2 Pills	95.75€ 91.19€
Cialis Generic	2.5mg	60 + 4 Pills	83.43€ 79.46€
Cialis Generic	5mg	180 + 10 Pills	159.65€ 152.05€
Cialis Generic	2.5mg	20 Pills	40.73€ 38.79€
Cialis Generic	40mg	120 + 8 Pills	206.98€ 197.12€
Cialis Super Active	20mg	120 + 16 Pills	382.15€ 363.95€
Cialis Generic	2.5mg	180 + 10 Pills	154.86€ 147.49€
Cialis Original	20mg	4 Pills	41.99€ 39.99€
Cialis Generic	20mg	60 + 6 Pills	117.76€ 112.15€

"Switching a medicine to over-the-counter is a highly regulated process that is data-driven and scientifically rigorous.

17.3 Cardiovascular Considerations

"Millions of men worldwide trust Cialis to treat ED. We are pleased to work with Sanofi to pursue a path that could allow more men who suffer from ED to obtain convenient access to a safe and reliable product without a prescription," said David Ricks, senior vice president, Lilly, and president, Lilly Bio-Medicines. "Switching a medicine to over-the-counter is a highly regulated process that is data-driven and scientifically rigorous. Cialis was first approved by the European Medicines Agency in 2002, then by the U.S. Food and Drug Administration in 2003, for the treatment of erectile dysfunction.

Alternatives for ED and BPH

Ultimately, Cialis has received approval in more than 120 countries for indications that vary by country, including erectile dysfunction and erectile dysfunction and the signs and symptoms of benign prostatic hyperplasia (BPH). Cialis reached $2.16 billion USD (€1.58 billion) in worldwide sales in 2013 and has recorded total global sales of more than $14 billion USD (€10.2 billion) since launch. To date, more than 45 million men worldwide have been treated with Cialis. Currently only available with a prescription, Cialis is a tablet taken to treat erectile dysfunction (ED), the signs and symptoms of benign prostatic hyperplasia (BPH), and both ED and the signs and symptoms of BPH. Cialis is the only PDE-5 inhibitor treatment that offers men a choice when it comes to treatment for erectile dysfunction – Cialis for use as needed and Cialis for once daily use.

Drug forms and strengths: 2.5 mg, 5 mg, 10 mg, 20 mg

It is important to note that Cialis is not to be taken with medicines called "nitrates" such as isosorbide dinitrate or isosorbide mononitrate which are often prescribed for chest pain; or with recreational drugs called "poppers" like amyl or butyl nitrite, as the combination may cause an unsafe drop in blood pressure; or if allergic to Cialis or Adcirca® (tadalafil), or any of its ingredients. Anyone who experiences any symptoms of an allergic reaction, such as rash, hives, swelling of the lips, tongue or throat, or difficulty breathing or swallowing, should call a healthcare provider or get help cialis 20 mg 8 tablets right away. ED is a medical condition in which a man has trouble getting or keeping an erection. It is very common: more than half of men over 40 years old have ED. Sanofi Consumer Healthcare is committed to providing consumers around the world with self-care solutions that empower them to better manage their health and well-being through leading brands in the areas of Allergy, Digestive health, Feminine care, Cough, cold, flu & sinus and Vitamins, minerals & supplements. Cialis was first approved by the European Medicines Agency in 2002, then by the U.S.

17.5 Potential for Drug Interactions When Taking CIALIS for Once Daily Use

We place people at the very heart of everything we do and strive to identify and fulfil their needs by delivering consumer insights-driven innovation, leveraging our medical & scientific heritage and our close collaboration with healthcare professionals, easing consumer access via switching relevant prescription medicines to over-the-counter solutions and applying the pharmaceutical quality standards delivered by our Group's global manufacturing network. In 2013, Sanofi Consumer healthcare achieved a €3.0 billion ($4.1 billion USD) turnover representing a 5.2% growth vs. 2012 (constant exchange rates) and ranked #3 worldwide consumer healthcare player (Nicholas Hall- 2013). Sanofi, a global healthcare leader, discovers, develops and distributes therapeutic solutions focused on patients' needs. Sanofi has core strengths in the field of healthcare with seven growth platforms: diabetes solutions, human vaccines, innovative drugs, consumer healthcare, emerging markets, animal health and the new Genzyme.

What if I miss a dose?

To learn more about Sanofi, please visit us at Lilly is a global healthcare leader that unites caring with discovery to make life better for people around the world. We were founded more than a century ago by a man committed to creating high-quality medicines that meet real needs, and today we remain true to that mission in all our work. Across the globe, Lilly employees work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to communities through philanthropy and volunteerism. To learn more about Lilly, please visit us at and Cialis is cialis online canada no prescription available via prescription only and is approved to treat erectile dysfunction, or ED (2.5 mg, 5 mg, 10 mg, 20 mg), and both ED and the signs and symptoms of benign prostatic hyperplasia, or BPH (5 mg). Taking Cialis with finasteride when starting BPH treatment has been studied for 26 weeks.

Related Products

Important Safety Information for CIALIS® (tadalafil) tablets What Is The Most Important Information I Should Know About CIALIS?Do not take CIALIS if you: take medicines called "nitrates" such as isosorbide dinitrate or isosorbide mononitrate which are often prescribed for chest pain as the combination may cause an unsafe drop in blood pressure use recreational drugs called "poppers" like amyl nitrite and butyl nitrite are allergic to CIALIS or ADCIRCA® (tadalafil), or any of its ingredients. What Should I Tell My Healthcare Provider Before Taking CIALIS?CIALIS is not right for everyone. Before taking CIALIS, tell your healthcare provider about all your medical problems, particularly if you have or ever had: heart problems such as chest pain (angina), heart failure, irregular heartbeats, or have had a heart attack high or low blood pressure or have high blood pressure that is not controlled liver or kidney problems or require dialysis retinitis pigmentosa, a rare genetic (runs in families) eye disease severe vision loss, including a condition called NAION a deformed penis shape or Peyronie's disease an erection that lasted more than 4 hours blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia Can Other Medicines Affect CIALIS?Tell your healthcare provider about all the medicines you take especially if you take: medicines called "nitrates" which are often prescribed for chest pain alpha-blockers often prescribed for prostate problems medicines for HIV or some types of oral antifungal medications some types of antibiotics such as clarithromycin, telithromycin, erythromycin (several brand names exist, please contact your healthcare provider to determine if you are taking this medicine) other medicines or treatments for erectile dysfunction (ED) CIALIS is also marketed as ADCIRCA for the treatment of pulmonary arterial hypertension. What Are The Possible Side Effects Of CIALIS?The most common side effects with CIALIS are: headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. Uncommon but serious side effects include:An erection that won't go away: If you get an erection lasting more than 4 hours, seek immediate medical help to avoid long-term injury. Food and Drug Administration in 2003, for the treatment of erectile dysfunction. Ultimately, Cialis has received approval in more than 120 countries for indications that vary by country, including erectile dysfunction and erectile dysfunction and the signs and symptoms of benign prostatic hyperplasia (BPH). Cialis reached $2.16 billion USD (€1.58 billion) in worldwide sales in 2013 and has recorded total global sales of more than $14 billion USD (€10.2 billion) since launch. To date, more than 45 million men worldwide have been treated with Cialis. Currently only available with a prescription, Cialis is a tablet taken to treat erectile dysfunction (ED), the signs and symptoms of benign prostatic hyperplasia (BPH), and both ED and the signs and symptoms of BPH. Cialis is the only PDE-5 inhibitor treatment that offers men a choice when it comes to treatment for erectile dysfunction – Cialis for use as needed and Cialis for once daily use. It is important to note that Cialis is not to be taken with medicines called "nitrates" such as isosorbide dinitrate or isosorbide mononitrate which are often prescribed for chest pain; or with recreational drugs called "poppers" like amyl or butyl nitrite, as the combination may cause an unsafe drop in blood pressure; or if allergic to Cialis or Adcirca® (tadalafil), or any of its ingredients. Anyone who experiences any symptoms of an allergic reaction, such as rash, hives, swelling of the lips, tongue or throat, or difficulty breathing or swallowing, should call a healthcare provider or get help cialis 20 mg 8 tablets right away. ED is a medical condition in which a man has trouble getting or keeping an erection.

14.4 CIALIS 5 mg for Once Daily Use for ED and BPH

Side effect details

1. They Look Different

It is very common: more than half of men over 40 years old have ED. Sanofi Consumer Healthcare is committed to providing consumers around the world with self-care solutions that empower them to better manage their health and well-being through leading brands in the areas of Allergy, Digestive health, Feminine care, Cough, cold, flu & sinus and Vitamins, minerals & supplements. We place people at the very heart of everything we do and strive to identify and fulfil their needs by delivering consumer insights-driven innovation, leveraging our medical & scientific heritage and our close collaboration with healthcare professionals, easing consumer access via switching relevant prescription medicines to over-the-counter solutions and applying the pharmaceutical quality standards delivered by our Group's global manufacturing network. In 2013, Sanofi Consumer healthcare achieved a €3.0 billion ($4.1 billion USD) turnover representing a 5.2% growth vs. 2012 (constant exchange rates) and ranked #3 worldwide consumer healthcare player (Nicholas Hall- 2013). Sanofi, a global healthcare leader, discovers, develops and distributes therapeutic solutions focused on patients' needs. Sanofi has core strengths in the field of healthcare with seven growth platforms: diabetes solutions, human vaccines, innovative drugs, consumer healthcare, emerging markets, animal health and the new Genzyme. To learn more about Sanofi, please visit us at Lilly is a global healthcare leader that unites caring with discovery to make life better for people around the world. We were founded more than a century ago by a man committed to creating high-quality medicines that meet real needs, and today we remain true to that mission in all our work.

Cialis 5 mg is a popular choice for men seeking a daily ED treatment.
It was approved by the FDA for this specific use in 2003.
The medication can also relieve symptoms of prostate enlargement.
Patients should monitor for any adverse reactions and report to their doctor.

Across the globe, Lilly employees work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to communities through philanthropy and volunteerism. To learn more about Lilly, please visit us at and Cialis is cialis online canada no prescription available via prescription only and is approved to treat erectile dysfunction, or ED (2.5 mg, 5 mg, 10 mg, 20 mg), and both ED and the signs and symptoms of benign prostatic hyperplasia, or BPH (5 mg). Taking Cialis with finasteride when starting BPH treatment has been studied for 26 weeks.

17.10 Sexually Transmitted Disease

Further information

protect a man or his partner from sexually transmitted diseases, including HIV serve as a male form of birth control For additional information, talk to your healthcare provider and please see the Full Prescribing Information, and Medication Guide. You may also learn more about Cialis at * The brand listed is a trademark of its respective owner and is not a trademark of Eli Lilly and Company. This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements are statements that are not historical facts. These statements include projections and estimates and their underlying assumptions, statements regarding plans, objectives, intentions and expectations with respect to future financial results, events, operations, services, product development and potential, and statements regarding future performance.

Dosage for benign prostatic hyperplasia (BPH)

Forward-looking statements are generally identified by the words "expects", "anticipates", "believes", "intends", "estimates", "plans" and similar expressions. Although Sanofi's and Lilly's management believe that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks and uncertainties, many of which are difficult to predict and generally beyond the control of the companies, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. In particular, there are no guarantees that regulatory authorities will approve Cialis for nonprescription use. Risks and uncertainties also include, among other things, the uncertainties inherent in research and development, future clinical data and analysis, including post marketing, decisions by regulatory authorities, such as the FDA or the EMA, regarding whether and when to approve any drug, device or biological application that may be filed for any such product candidates as well as their decisions regarding labelling and other matters that could affect the availability or commercial potential of such product candidates, the absence of guarantee that the product candidates if approved will be commercially successful, the future approval and commercial success of therapeutic alternatives, the Companies' ability to benefit from external growth opportunities, trends in exchange rates and prevailing interest rates, the impact of cost containment policies and subsequent changes thereto, the average number of shares outstanding as well as those discussed or identified in the public filings with the SEC and the AMF made by Sanofi, including those listed under "Risk Factors" and "Cautionary Statement Regarding Forward-Looking Statements" in Sanofi's annual report on Form 20-F for the year ended December 31, 2013, and in the public filings with the SEC made by Lilly, including those listed under "risk Factors" in Lilly's annual report on Form 10-K for the year ended December 31, 2013. Other than as required by applicable law, the companies do not undertake any obligation to update or revise any forward-looking information or statements.

Generic version

Program Cialis 20 mg: 3,900 baht (4 Tablets) Program Cialis 5 mg: 5,900 baht (28 Tablets) Indication: Used to treat erectile dysfunction (ED) and can also be prescribed for symptoms of benign prostatic hyperplasia (BPH/enlarged prostate). Before taking CIALIS, tell your healthcare provider about all your medical problems, particularly if you have or ever had: heart problems such as chest pain (angina), heart failure, irregular heartbeats, or have had a heart attack high or low blood pressure or have high blood pressure that is not controlled liver or kidney problems or require dialysis retinitis pigmentosa, a rare genetic (runs in families) eye disease severe vision loss, including a condition called NAION a deformed penis shape or Peyronie's disease an erection that lasted more than 4 hours blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia Can Other Medicines Affect CIALIS?Tell your healthcare provider about all the medicines you take especially if you take: medicines called "nitrates" which are often prescribed for chest pain alpha-blockers often prescribed for prostate problems medicines for HIV or some types of oral antifungal medications some types of antibiotics such as clarithromycin, telithromycin, erythromycin (several brand names exist, please contact your healthcare provider to determine if you are taking this medicine) other medicines or treatments for erectile dysfunction (ED) CIALIS is also marketed as ADCIRCA for the treatment of pulmonary arterial hypertension. What Are The Possible Side Effects Of CIALIS?The most common side effects with CIALIS are: headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose.

Parameter	Value	Notes
Absorption Rate	Peak plasma levels in 2 hours
Half-life	Approximately 17.5 hours	Duration of action
Metabolism	Liver via CYP3A4 enzymes
Excretion	Mainly in feces; minor in urine

Uncommon but serious side effects include:An erection that won't go away: If you get an erection lasting more than 4 hours, seek immediate medical help to avoid long-term injury. protect a man or his partner from sexually transmitted diseases, including HIV serve as a male form of birth control For additional information, talk to your healthcare provider and please see the Full Prescribing Information, and Medication Guide. You may also learn more about Cialis at * The brand listed is a trademark of its respective owner and is not a trademark of Eli Lilly and Company. This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, as amended.

Cialis 5 mg does not cure erectile dysfunction but manages its symptoms.
The medication is often preferred for its long-lasting effects.
Dosing may be adjusted based on individual response and tolerance.
Use Cialis 5 mg exactly as recommended for safety and effectiveness.

Forward-looking statements are statements that are not historical facts.

Cialis 5 mg's active ingredient, tadalafil, has a half-life of about 17.5 hours.
The drug's long half-life allows spontaneity in sexual activity.
Cialis 5 mg is also used for pulmonary arterial hypertension under different dosing.
Always follow the specific dosing and usage advice given by your doctor.

These statements include projections and estimates and their underlying assumptions, statements regarding plans, objectives, intentions and expectations with respect to future financial results, events, operations, services, product development and potential, and statements regarding future performance.

Patients should avoid grapefruit or grapefruit juice while on Cialis 5 mg.
The medication can be used by men with certain cardiac conditions after consultation.
Proper hydration and lifestyle changes can improve treatment outcomes.
Cialis 5 mg has been shown to effectively improve erectile function in many users.

Forward-looking statements are generally identified by the words "expects", "anticipates", "believes", "intends", "estimates", "plans" and similar expressions.

14.1 CIALIS for Use as Needed for ED

Although Sanofi's and Lilly's management believe that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks and uncertainties, many of which are difficult to predict and generally beyond the control of the companies, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. In particular, there are no guarantees that regulatory authorities will approve Cialis for nonprescription use.

Ingredient	Quantity per Tablet	Purpose
Tadalafil	5 mg	Active ingredient for erectile dysfunction
Microcrystalline Cellulose	50 mg	Filler/biller
Magnesium Stearate	2 mg	Lubricant
Lactose Monohydrate	35 mg	filler
Croscarmellose Sodium	3 mg	Disintegrant
Hypromellose	5 mg	Coating agent

Risks and uncertainties also include, among other things, the uncertainties inherent in research and development, future clinical data and analysis, including post marketing, decisions by regulatory authorities, such as the FDA or the EMA, regarding whether and when to approve any drug, device or biological application that may be filed for any such product candidates as well as their decisions regarding labelling and other matters that could affect the availability or commercial potential of such product candidates, the absence of guarantee that the product candidates if approved will be commercially successful, the future approval and commercial success of therapeutic alternatives, the Companies' ability to benefit from external growth opportunities, trends in exchange rates and prevailing interest rates, the impact of cost containment policies and subsequent changes thereto, the average number of shares outstanding as well as those discussed or identified in the public filings with the SEC and the AMF made by Sanofi, including those listed under "Risk Factors" and "Cautionary Statement Regarding Forward-Looking Statements" in Sanofi's annual report on Form 20-F for the year ended December 31, 2013, and in the public filings with the SEC made by Lilly, including those listed under "risk Factors" in Lilly's annual report on Form 10-K for the year ended December 31, 2013. Other than as required by applicable law, the companies do not undertake any obligation to update or revise any forward-looking information or statements. Program Cialis 20 mg: 3,900 baht (4 Tablets) Program Cialis 5 mg: 5,900 baht (28 Tablets) Indication: Used to treat erectile dysfunction (ED) and can also be prescribed for symptoms of benign prostatic hyperplasia (BPH/enlarged prostate).